Prinzmetal's or Prinzmetal Angina, Variant Angina and Angina Inversa
Unlike typical angina – which is often triggered by exertion or emotional stress – Prinzmetal’s angina almost always occurs when a person is at rest, usually between midnight and early morning. These attacks can be very painful.
Prinzmetal angina may also be referred to as:
- Variant angina
 - Prinzmetal's variant angina
 - Angina inversa
 
See an illustration of angina.
Causes
The pain from variant angina is caused by a spasm in the coronary arteries, which supply blood to the heart muscle.
The coronary arteries can spasm because of:
- Exposure to cold weather
 - Stress
 - Medicines that tighten or narrow blood vessels
 - Smoking
 - Cocaine use
 
Symptoms
The pain/discomfort:
- Usually occurs while resting and during the night or early morning.
 - Is usually severe.
 - Can be relieved by taking medication.
 
Treatment
Medicines can help control the spasms. Drugs such as calcium channel blockers and nitrates are the mainstays of treatment.
Prinzmetal's angina is a chronic condition that will need to be followed by your health care team even though the prognosis is generally good.